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In the neurogenic niche, astrocytes express ciliary neurotrophic factor (CNTF), while the receptor, CNTFR, is predominantly expressed in neural progenitor cells and hippocampal neurons [22]

A: Some studies suggest activity when administered orally or via injection in animal models, but this is still under investigation and not clinically validated

Interestingly, selenium deficiency in rodents was found to have little impact on DIO activities as it appears that selenium is being supplied in priority for adequate synthesis of DIOs at the expense of other selenoenzymes (10)

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